Monday, April 02, 2007
08:30 am – 09:00 am
- Opening Ceremony
- Location: Hall I (Room A)
- INVITED LECTURE – 1 (Co-Chairs: Yutaka Kohgo, Elizabeth Theil)
- 09:00 am – 09:45 am
- IL-02: POSTTRANSLATIONAL PROCESSING OF HEPCIDIN IN HUMAN HEPATOCYTES IS MEDIATED BY A FURIN-TYPE PROHORMONE CONVERTASE
- T. Ganz, PhD, MD and E. Valore, MS, Depts. of Medicine and Pathology, David Geffen School of Medicine, UCLA (Presented By: T. Ganz, PhD, MD)
- 10:30 am – 11:00 am
- Break
- INVITED LECTURE – 2 (Co-Chairs: Graca Porto, Prem Ponka)
- 11:00 am – 11:30 am
- IL-03: BMP/Hemojuvelin
- Herbert Y. Lin, MD, PhD
- 11:30 am – 12:00 am
- IL-04: eALA, Sideroblastic Anemia
- Masayuki Yamamoto, MD
- 12:00 am – 01:30 pm
- Lunch
- 01:30 pm – 04:10 pm
- NOVARTIS SYMPOSIUM: IRON LOADING AND ITS CLINICAL IMPLICATIONS (Co-Chairs: Antonello Pietrangelo, Chaim Hershko)
- 01:30 pm – 01:35 pm
- Welcome and Introductions
- Antonello Pietrangelo, MD, PhD
- 01:35 pm – 02:05 pm
- Mechanism of Iron Overloading and Toxicity
- Greg Anderson, BSc, MSc, PhD
- 02:05 pm – 02:35 pm
- Imaging in the Diagnosis and Management of Transfusion Iron Overload
- J. Wood
- 02:35 pm – 03:05 pm
- Treatment and Management of Transfusion Iron Overload
- John Porter
- 03:05 pm – 03:35 pm
- Management of Genetic Hemachromatosis
- Pierre Brissot, MD
- 03:35 pm – 04:05 pm
- Iron Chelation Beyond Transfusion Iron Overload
- Antonello Pietrangelo, MD, PhD
- 04:05 pm – 04:10 pm
- Closing Remarks
- Chaim Hershko, MD
- 04:15 pm – 05:15 pm
- EVENING SEMINAR (Chairs: Teiryo Maeda) co-sponsored by Kirin Brewery Co., Ltd.
- 04:15 pm – 04:45 pm
- Rice Genome Information as a Basic Tool in Modern Plant Biology
- Takuji Sasaki, Vice President, National Institute of Agrobiological Sciences (NIAS)
- 04:45 pm -05:15 pm
- Exploring iron regulatory networks: integration of biocomputational,biochemical and genomic approaches
- Matthias Hentze
- 01:30 pm – 02:45 pm
- Concurrent Session 1: Non-Vertebrate, Immunology (Co-Chairs: Caroline Philpott, Koji Nakayama)
- Location: Hall II (Room C-1)
- 01:30 pm
- O-01: IDENTIFICATION OF UGA3 AS AN IRON-REGULATED TRANSCRIPTION FACTOR CONTROLLING THE ACTIVITY OF THE GABA SHUNT IN SACCHAROMYCES CEREVISIAE
- C. Philpott and B. Mukhopadhyay, Liver Diseases Branch, NIDDK, NIH (Presented By: C. Philpott)
- 01:45 pm
- O-02: IRON HOMEOSTASIS IN ARABIDOPSIS: VACUOLES AND BEYOND
- S. Kim, T. Punshon, A. Lanzirotti, L. Li, J. Kaplan and M. Guerinot, Dartmouth College (Presented By: S. Kim)
- 02:00 pm
- O-03: CLONING OF A NOVEL GLUTATHIONE TRANSPORTER, OSGTL1 FROM RICE
- K. BASHIR, MPhil, Y. Ishimaru, PhD, T. Aoyama, S. Nagasaka, PhD, M. Takahashi, PhD, H. Nakanishi, PhD, S. Mori, PhD and N. Nishizawa, PhD, The University of Tokyo (Presented By: K. BASHIR, MPhil)
- 02:15 pm
- O-04: KNOCKOUT OF FRATAXIN GENE CAUSES EMBRYO LETHALITY IN ARABIDOPSIS
- I. Murgia, PhD, V. Vazzola, PhD student, A. Losa, PhD and C. Soave, Prof, University Milano (Presented By: I. Murgia, PhD)
- 02:30 pm
- O-05: IDENTIFICATION OF A SURFACE-MEDIATED PATHWAY FOR IRON UPTAKE IN THE PARASITIC TREMATODE SCHISTOSOMA MANSONI
- A. Glanfield, BSc (Hons), D. Smyth, PhD, D. McManus, PhD, DSc and M. Jones, PhD,Queensland Institute of Medical Research (Presented By: A. Glanfield, BSc (Hons))
- 02:45 pm – 04:00 pm
- Concurrent Session 2: Iron Transport, Storage (1) (Co-Chairs: Maria Linder, Masahiko Akita)
- Location: Hall II (Room C-1)
- 02:45 pm
- O-06: FERRITIN-MEDIATED IRON TRANSPORT VIA TIM-2 IN MOUSE KIDNEY CELLS
- S. Torti, PhD, J. Han, PhD, W. Seaman, PhD and F. Torti, MD, Wake Forest University Health Sciences (Presented By: S. Torti, PhD)
- 03:00 pm
- O-07: NEW EVIDENCES FOR THE INVOLVEMENT OF PKCZ PATHWAY IN RESPONSE TO FERRITIN IN HEPATIC STELLATE CELLS USING SHRNA COUPLED TO BACULOVIRUS DELIVERY SYSTEM
- M. Philippe, Dr, R. Ruddell, Dr, R. Bing and G. Ramm, assoc Prof, QIMR hepatic fibrosis group (Presented By: M. Philippe, Dr)
- 03:15 pm
- O-08: A FLUORESCENT METAL-SENSOR STUDY PROVIDING EVIDENCE FOR IRON TRANSPORT IN INTESTINAL EPITHELIAL CELLS BY TRANSCYTOSIS.
- Y. Ma, MD, PhD, Y. Okazaki, MD, PhD, M. Yeh, MS, K. Yeh, PhD and J. Glass, MD, Feist-Weiller Cancer Center, LSUHSC (Presented By: Y. Okazaki, MD, PhD)
- 03:30 pm
- O-09: SUSTAINED HYDROGEN PEROXIDE INDUCES IRON UPTAKE BY TRANSFERRIN RECEPTOR-1 INDEPENDENT OF THE IRP/IRE NETWORK
- B. Andriopoulos, S. Hegedsch, J. Mangin, A. Welker, H. Riedel, U. Hebling, J. Wang, K. Pantopoulos and S. Mueller, Lady Davis Institute for Medical Research (Presented By: K. Pantopoulos)
- 03:45 pm
- O-10: HYPOFERREMIA BUT NO CHANGE IN INTESTINAL IRON TRANSPORT IN MICE FOLLOWING EXPOSURE TO HEPCIDIN
- M. Mascarenhas, BSc, T. Chaston, PhD, S. Srai, PhD and P. Sharp, PhD, King’s College London (Presented By: T. Chaston, PhD)
- 01:30 pm – 02:45 pm
- Concurrent Session 3: IRE/IRP (Co-Chairs: Kostas Pantapoulos, Koichi Orino)
- Location: Hall III (Room C-2)
- 01:30 pm
- O-11: FUNCTION OF THE IRP/IRE REGULATORY NETWORK IN THE DUODENUM
- B. Galy, PhD, D. Ferring-Appel, StaatlGepruft, M. Sanchez, PhD, M. Muckenthaler, PhD, H. Grne, PhD and M. Hentze, MD, European Molecular Biology Laboratory (Presented By: B. Galy, PhD)
- 01:45 pm
- O-12: TISSUE-SPECIFIC FUNCTIONS OF IRON REGULATORY PROTEIN (IRP)-2 IN VIVO
- D. Ferring-Appel, B. Galy, PhD and M. Hentze, MD, European Molecular Biology Laboratory (Presented By: D. Ferring-Appel)
- 02:00 pm
- O-13: NEW DEVELOPMENTS IN THE BIOCHEMISTRY OF IRON REGULATORY PROTEINS
- J. Moulis, Dr, C. Dycke, PhD, A. Martelli, PhD and E. Rousselet, MSc, CEA-Grenoble (Presented by: J. Moulis, Dr)
- 02:15 pm
- O-14: CONTROL OF IRON REGULATORY PROTEIN 1 BY PHOSPHORYLATION AND PROTEIN DEGRADATION
- R. Eisenstein, PhD, A. Vasanthakumar, MS, S. Anderson, MS, DVM and S. Clarke, PhD, University of Wisconsin (Presented By: R. Eisenstein, PhD)
- 02:30 pm
- O-15: IRE-DEPENDENT, DIFFERENTIAL REGULATION OF FERRITIN H AND FERRITIN L MRNA
- R. Leipuviene, PhD, J. Long, PhD, Z. Jenkins, PhD and E. Theil, PhD, CHORI and UC-Berkeley (Presented By: E. Theil, PhD)
- 02:45 pm – 04:00 pm
- Concurrent Session 4: FeS, HO-1 (Co-Chairs: Sonia Levi, Masayoshi Kobune)
- Location: Hall III (Room C-2)
- 02:45 pm
- O-16: MOBILIZATION OF INTRACELLULAR IRON FOR BIOGENESIS OF IRON-SULFUR
- H. Ding, PhD, J. Bitoun, Bsc and J. Yang, Ms, Louisiana State University (Presented By: H. Ding, PhD)
- 03:00 pm
- O-17: DOWN-REGULATION OF COMPONENTS OF THE FE-S CLUSTER ASSEMBLY MACHINERY IN INFLAMMATORY MACROPHAGES
- C. Bouton, PhD, F. CANAL, PHD student, C. FOSSET, PhD, M. CHAUVEAU, technician and J. DRAPIER, PhD, Institut de Chimie des Substances Naturelles-CNRS (Presented By: C. Bouton, PhD)
- 03:15 pm
- O-18: THE ROLE OF MITOCHONDRIAL AND CYTOSOLIC IRON-SULFUR CLUSTER BIOGENESIS IN MAINTAINENCE OF MAMMALIAN IRON HOMEOSTASIS
- W. Tong, PhD, K. Li, PhD, H. Uhrigshardt, PhD and T. Rouault, MD, National Institute of Child Health and Human Development (Presented By: W. Tong, PhD)
- 03:30 pm
- O-19: HEME AND IRON HOMEOSTASIS ARE LINKED WITH THAT OF COPPER VIA THE HEMOPEXIN-HEME OXYGENASE-1 AXIS
- K. Rish, MS, R. Helston, PhD and A. Smith, PhD, University of Missouri-Kansas City (PresentedBy: A. Smith, PhD)
- 03:45 pm
- O-20: ANALYIS OF PROTEINS INVOLVED IN MAMMALIAN FE/S BIOSYNTHESIS BY SIRNA SILENCING
- P. Cavadini, PhD, M. Poli, PhD, S. Luscieti, PhD and P. Arosio, Dipartimento Materno Infantile e Tecnologie Biomediche, University of Brescia (Presented By: P. Arosio)
